CSH Retroviruses
Published:
This week I attended the virtual CSH Retroviruses virtual meeting. The meeting covers the retrovirus lifecycle, starting from viral cell entry to release. The meeting was great, and here are a few highlights I put together for you.
Published highlights:
- Capsid Uncoating and Nuclear Entry
- Ryan Burdick from the Pathak lab reveals that nuclear uncoating of HIV-1 occures near sites of integration, read more at PNAS 2020.
- Mirijana Persaud from the Diaz-Griffero lab explains how Cyclophilin A prevents TRIM5α restriction of HIV, read more at Cell Reports 2020.
- Accessory Proteins and Antagonism of Restriction Factors
- Molly Ohainle from the Emerman lab presents how TRIM34 restricts HIV with capsid mutant N74D, read more at PLOS Pathogens 2020.
- Mollie McDonnell from the Emerman lab talks about super restriction factors and double domains of APOBEC3, read more at mBio 2020.
- Ruth Serra- Moreno illuminates how Nef counteracts autophagy restriction of HIV, read more at Autophagy 2020.
- Reverse Transcription and Integration
- Very exciting talks! But as most of them are still unpublished, I’m looking forward to reading them when they are out!
- Fantastic keynote by Anna Maria Skalka. It was so fascinating to learn about her work in phages, retroviruses, integrase, protease, recombination, reversetranscription, and RNAviruses. On a personal note, her success story is what gives me hope and excitement for our future.
- Follow more HIV scientists on twitter: @elena_ilka, @AshwanthFrancis, @MollyOhainle, @molliegoesviral, @HaiderTahfhima,@Sara_Sawyer_, @Jolly_lab, @ProfAmbrose, @memerman, @HoLabHIV,@GFPvirus, @puglisilab, and you can find me at @MiriKrupkin.
See you soon, Miri